Local FDR estimation via locfdr

Thin extender over locfdr::locfdr for Efron's empirical-Bayes local false-discovery-rate estimation from a vector of z-scores (Efron, 2004; Efron, 2010).

Usage

morie_locfdr_estimate(zz, ...)

Arguments

zz

Numeric vector of test statistics (typically z-scores) for the locfdr empirical-null fit.

...

Further arguments forwarded to locfdr::locfdr (e.g. bre, df, pct, pct0, nulltype, type, plot, mult, mlests, main, sw).

Value

A list with $method = "locfdr::locfdr" and $raw (the locfdr object with the fitted local-FDR curve, empirical-null parameters, and the fdr / Fdrleft / Fdrright summaries).

Examples

if (FALSE) { # \dontrun{
  if (requireNamespace("locfdr", quietly = TRUE)) {
    set.seed(1)
    zz <- c(stats::rnorm(900), stats::rnorm(100, mean = 3))
    morie_locfdr_estimate(zz)
  }
} # }