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Thin extender over fdrtool::fdrtool for the Strimmer (2008) shrinkage estimator of local and tail-area false-discovery rates, q-values, and the underlying null-distribution scale parameter.

Usage

morie_fdr_qvalues(x, statistic = "normal", ...)

Arguments

x

Numeric vector of test statistics or p-values, as appropriate to statistic.

statistic

Character; the type of statistic in x. One of "normal" (default), "correlation", "pvalue", or "studentt".

...

Further arguments forwarded to fdrtool::fdrtool (e.g. plot, color.figure, verbose, cutoff.method, pct0).

Value

A list with $method = "fdrtool::fdrtool" and $raw (the fdrtool return list with pval, qval, lfdr, and param).

Examples

# \donttest{
  if (requireNamespace("fdrtool", quietly = TRUE)) {
    set.seed(1)
    x <- c(stats::rnorm(900), stats::rnorm(100, mean = 3))
    morie_fdr_qvalues(x, statistic = "normal")
  }
#> Step 1... determine cutoff point
#> Step 2... estimate parameters of null distribution and eta0
#> Step 3... compute p-values and estimate empirical PDF/CDF
#> Step 4... compute q-values and local fdr
#> Step 5... prepare for plotting

#> 
#> $method
#> [1] "fdrtool::fdrtool"
#> 
#> $raw
#> $raw$pval
#>    [1] 5.785364e-01 8.706362e-01 4.586844e-01 1.571694e-01 7.701342e-01
#>    [6] 4.668761e-01 6.655669e-01 5.126427e-01 6.096390e-01 7.865364e-01
#>   [11] 1.800470e-01 7.295656e-01 5.817016e-01 4.953687e-02 3.184922e-01
#>   [16] 9.682159e-01 9.885451e-01 4.026090e-01 4.664674e-01 5.984317e-01
#>   [21] 4.151143e-01 4.879461e-01 9.472804e-01 7.771374e-02 5.825620e-01
#>   [26] 9.603028e-01 8.901174e-01 1.921561e-01 6.715572e-01 7.109203e-01
#>   [31] 2.282636e-01 9.273737e-01 7.310135e-01 9.619450e-01 2.220320e-01
#>   [36] 7.128680e-01 7.266039e-01 9.580525e-01 3.293244e-01 4.985547e-01
#>   [41] 8.840039e-01 8.222322e-01 5.365424e-01 6.215638e-01 5.413508e-01
#>   [46] 5.304040e-01 7.464663e-01 4.955449e-01 9.206414e-01 4.345998e-01
#>   [51] 7.240655e-01 5.873157e-01 7.622735e-01 3.165892e-01 2.038104e-01
#>   [56] 7.905937e-02 7.446945e-01 3.544912e-01 6.134090e-01 9.046708e-01
#>   [61] 3.319674e-02 9.722416e-01 5.407733e-01 9.801893e-01 5.098210e-01
#>   [66] 8.670424e-01 1.094671e-01 1.937319e-01 8.918993e-01 5.402716e-02
#>   [71] 6.732658e-01 5.289805e-01 5.881098e-01 4.074809e-01 2.662709e-01
#>   [76] 7.960617e-01 6.942454e-01 9.992179e-01 9.474383e-01 6.011324e-01
#>   [81] 6.140636e-01 9.045837e-01 2.961623e-01 1.766757e-01 5.984041e-01
#>   [86] 7.678012e-01 3.458186e-01 7.873581e-01 7.428182e-01 8.127680e-01
#>   [91] 6.304501e-01 2.841211e-01 3.034719e-01 5.346442e-01 1.593785e-01
#>   [96] 6.204222e-01 2.576131e-01 6.112025e-01 2.774983e-01 6.746315e-01
#>  [101] 5.822330e-01 9.702081e-01 4.192155e-01 8.885525e-01 5.615980e-01
#>  [106] 1.170710e-01 5.250641e-01 4.195972e-01 7.333399e-01 1.357745e-01
#>  [111] 5.729205e-01 6.822643e-01 2.040445e-01 5.639249e-01 8.540918e-01
#>  [116] 7.275905e-01 7.765929e-01 8.045129e-01 6.612166e-01 8.750460e-01
#>  [121] 6.536692e-01 2.336638e-01 8.490868e-01 8.734906e-01 9.292037e-01
#>  [126] 5.274032e-01 9.479868e-01 9.733771e-01 5.455247e-01 7.736874e-01
#>  [131] 9.574540e-01 6.015191e-01 6.374138e-01 1.781495e-01 7.857389e-01
#>  [136] 1.730445e-01 7.895475e-01 6.394516e-01 5.630875e-01 9.597601e-01
#>  [141] 8.958196e-02 2.967792e-01 1.398213e-01 6.810378e-01 3.223840e-01
#>  [146] 5.055339e-01 6.419140e-02 9.876923e-01 2.540115e-01 1.457111e-01
#>  [151] 6.897349e-01 9.868687e-01 7.779012e-01 4.098625e-01 1.871546e-01
#>  [156] 3.403600e-01 3.751860e-01 5.816857e-01 2.195687e-01 9.738993e-02
#>  [161] 7.061969e-01 8.323985e-01 3.479172e-01 4.318336e-01 5.829165e-01
#>  [166] 5.042775e-02 8.210834e-01 2.065148e-01 8.981094e-01 8.539821e-01
#>  [171] 4.069161e-02 9.252498e-01 6.852898e-01 9.454534e-01 7.670897e-01
#>  [176] 9.754337e-01 4.848899e-01 6.572767e-02 3.622604e-01 2.841049e-01
#>  [181] 2.748738e-01 3.829387e-01 8.453742e-01 1.932169e-01 6.440597e-01
#>  [186] 8.880440e-01 1.940263e-01 4.969207e-01 7.028314e-01 4.115032e-01
#>  [191] 8.752043e-01 7.214705e-01 5.164054e-01 4.615149e-01 2.840354e-01
#>  [196] 3.527197e-01 2.012553e-01 3.676794e-01 7.148658e-01 7.354168e-01
#>  [201] 7.165694e-01 1.342238e-01 1.594429e-01 7.691851e-01 4.271451e-02
#>  [206] 2.676933e-02 5.541601e-01 6.312019e-01 9.905195e-01 6.510157e-01
#>  [211] 8.841073e-01 7.091025e-01 7.226428e-01 2.243406e-01 3.810351e-01
#>  [216] 1.777637e-01 7.842510e-01 2.664020e-01 5.690007e-01 9.683746e-01
#>  [221] 1.242993e-01 9.984916e-01 5.762062e-01 7.623757e-01 3.050707e-01
#>  [226] 1.098246e-01 7.690332e-01 1.545247e-01 8.611847e-01 8.154681e-01
#>  [231] 3.820056e-01 1.041241e-02 5.700598e-01 6.129183e-01 9.577629e-01
#>  [236] 9.306218e-01 6.189619e-01 2.927434e-01 3.307546e-01 9.962189e-01
#>  [241] 5.305113e-01 3.591314e-01 8.429066e-01 4.358523e-01 3.024056e-01
#>  [246] 7.611324e-02 6.290197e-01 8.206395e-01 8.828857e-01 3.655065e-01
#>  [251] 9.038508e-01 7.180499e-01 9.507474e-01 8.261650e-01 5.373684e-01
#>  [256] 3.094165e-01 3.308858e-02 6.115295e-01 7.396654e-01 7.060867e-01
#>  [261] 3.990412e-01 7.299696e-01 8.009348e-01 4.470574e-01 1.272782e-01
#>  [266] 8.107349e-01 7.081198e-01 2.916648e-01 7.691003e-01 4.046092e-01
#>  [271] 8.183909e-01 7.265445e-01 4.500054e-01 1.881298e-02 8.899659e-01
#>  [276] 3.162276e-01 4.236274e-02 5.111155e-01 2.431240e-01 4.146950e-01
#>  [281] 7.240494e-01 7.178106e-01 2.402668e-01 5.340503e-01 6.066407e-01
#>  [286] 3.746880e-01 5.534995e-01 4.019370e-01 7.005364e-01 3.727411e-01
#>  [291] 7.293820e-01 7.385637e-01 8.285828e-01 2.059538e-01 1.147800e-01
#>  [296] 9.050972e-01 4.971921e-01 3.969997e-01 9.642345e-01 7.862452e-01
#>  [301] 4.280762e-01 3.530351e-01 8.044088e-02 7.337093e-01 1.424154e-01
#>  [306] 1.799227e-01 9.413510e-01 6.149660e-01 3.635906e-01 7.745455e-01
#>  [311] 3.547319e-01 9.299877e-01 6.871561e-01 5.608824e-01 9.745876e-01
#>  [316] 3.430754e-01 6.677943e-01 9.145440e-01 2.511289e-01 6.611366e-01
#>  [321] 2.461241e-01 1.843304e-01 4.700127e-01 9.730074e-02 6.690502e-01
#>  [326] 6.858525e-01 7.539869e-01 8.798291e-01 4.435538e-01 5.469577e-01
#>  [331] 7.717664e-01 1.640970e-01 7.445406e-01 2.262991e-01 7.668998e-01
#>  [336] 5.158313e-01 4.012399e-01 9.968877e-01 7.547132e-01 6.385544e-01
#>  [341] 5.119209e-01 3.456564e-01 8.271691e-01 7.973942e-01 4.459567e-02
#>  [346] 2.115429e-01 4.166175e-01 8.653078e-01 4.762593e-01 9.417658e-02
#>  [351] 1.912121e-01 5.481164e-01 7.361609e-01 8.642482e-01 1.617423e-01
#>  [356] 5.969957e-01 2.980151e-01 8.902246e-01 8.882246e-02 8.625329e-01
#>  [361] 2.151558e-02 2.439280e-01 5.730373e-01 7.029846e-01 8.806484e-01
#>  [366] 5.871986e-01 5.474834e-01 6.145102e-01 6.116520e-01 2.266885e-01
#>  [371] 7.303129e-01 8.053359e-01 4.654585e-01 9.513222e-01 3.004568e-01
#>  [376] 9.941211e-01 9.090271e-01 8.970736e-01 8.844328e-01 1.178470e-01
#>  [381] 4.988864e-01 3.243344e-01 4.129706e-01 8.841311e-01 3.058019e-01
#>  [386] 9.600253e-01 5.899041e-02 7.597563e-01 9.116812e-02 4.719402e-01
#>  [391] 2.403571e-01 5.851129e-01 3.330118e-01 7.857068e-01 9.221816e-01
#>  [396] 4.124111e-01 1.577861e-01 9.681615e-01 5.259775e-01 4.429278e-01
#>  [401] 3.406975e-01 9.275899e-02 5.928413e-01 7.288828e-01 7.120565e-01
#>  [406] 7.390408e-01 7.450908e-01 7.931676e-01 2.010482e-01 5.362064e-01
#>  [411] 7.306828e-01 5.628231e-01 3.185604e-01 4.935402e-01 6.523079e-01
#>  [416] 6.424085e-01 3.667810e-01 8.237483e-01 2.047683e-01 1.296188e-01
#>  [421] 2.031655e-01 5.287340e-01 9.539873e-01 1.186999e-01 6.134069e-01
#>  [426] 1.527774e-01 1.465293e-01 4.893756e-01 5.696412e-01 5.458366e-01
#>  [431] 7.137756e-02 6.568675e-01 1.743491e-01 9.823145e-01 5.989964e-01
#>  [436] 8.604865e-01 4.289375e-01 9.818070e-01 5.657449e-01 5.665257e-01
#>  [441] 7.004506e-01 1.159719e-01 9.870810e-01 4.494961e-01 8.556350e-01
#>  [446] 7.642613e-03 2.257289e-01 7.068548e-01 8.336742e-01 3.775825e-02
#>  [451] 3.937652e-01 5.919655e-01 5.043678e-01 1.677474e-01 1.973017e-01
#>  [456] 9.601593e-01 6.514878e-01 6.283586e-02 3.731204e-01 6.347091e-01
#>  [461] 6.878738e-01 5.483318e-02 2.692906e-01 5.974486e-01 9.965440e-01
#>  [466] 8.043431e-01 5.313279e-01 5.775888e-01 1.893119e-01 3.366733e-01
#>  [471] 4.708080e-01 1.511218e-01 9.225358e-01 6.958195e-01 2.309060e-01
#>  [476] 2.422785e-01 7.465988e-01 8.359615e-01 2.897044e-01 9.802545e-01
#>  [481] 7.513621e-01 3.091693e-01 6.463521e-01 7.481176e-01 3.712253e-02
#>  [486] 3.004292e-02 8.824782e-01 3.547066e-01 8.019593e-02 6.481037e-01
#>  [491] 3.334971e-01 4.276685e-02 4.322519e-01 9.215143e-01 7.278707e-04
#>  [496] 3.254331e-01 7.850511e-01 3.263133e-01 7.578611e-01 4.387004e-01
#>  [501] 9.453474e-01 7.923534e-01 2.940538e-01 9.920101e-01 3.792237e-01
#>  [506] 1.575113e-01 2.234951e-01 8.248208e-01 3.038796e-01 3.231208e-01
#>  [511] 2.494765e-02 4.065753e-01 3.910447e-01 9.664096e-01 7.203254e-01
#>  [516] 8.373494e-01 7.079955e-01 7.400712e-01 7.455104e-01 2.912640e-01
#>  [521] 5.132123e-01 7.965952e-01 4.326512e-01 8.536565e-01 9.662389e-01
#>  [526] 1.352301e-01 8.982308e-01 2.952912e-01 5.456783e-01 8.989179e-01
#>  [531] 2.903669e-01 2.998089e-01 9.440073e-01 6.886985e-01 1.453621e-01
#>  [536] 4.949509e-01 7.879196e-01 2.557000e-01 5.933163e-01 7.854222e-01
#>  [541] 7.106056e-01 7.528182e-01 6.488629e-01 9.868350e-01 2.423359e-01
#>  [546] 9.534474e-01 5.345961e-01 6.337270e-01 5.088046e-02 7.281461e-01
#>  [551] 6.594354e-01 8.419394e-01 3.218540e-01 7.261349e-01 1.693326e-01
#>  [556] 5.096836e-01 3.866776e-02 4.713530e-01 6.566450e-01 6.505187e-01
#>  [561] 2.811431e-01 9.840398e-01 5.340459e-01 6.023914e-01 5.905553e-01
#>  [566] 3.308150e-01 8.262719e-01 8.872404e-01 5.789461e-01 4.245900e-01
#>  [571] 3.779788e-01 4.513932e-01 4.749322e-01 6.783930e-01 4.518356e-01
#>  [576] 3.815503e-01 6.097391e-01 7.256129e-02 8.182975e-02 3.015930e-01
#>  [581] 2.222135e-01 8.817947e-01 1.599588e-01 1.367744e-01 6.650078e-01
#>  [586] 4.358702e-01 8.977759e-01 6.775032e-01 7.386539e-01 4.997572e-01
#>  [591] 7.947969e-01 9.048207e-01 2.164480e-01 3.577943e-01 6.080090e-02
#>  [596] 4.956878e-01 4.692185e-01 6.989569e-01 4.223966e-01 4.986051e-01
#>  [601] 7.623092e-01 1.827573e-01 6.394340e-01 6.306572e-01 9.035337e-01
#>  [606] 3.134412e-01 1.844517e-01 8.429724e-01 7.588541e-02 8.441394e-01
#>  [611] 8.841094e-01 7.680226e-01 7.326572e-01 2.148346e-01 1.765471e-02
#>  [616] 7.071292e-01 7.911693e-01 1.119691e-01 8.259275e-01 8.264140e-01
#>  [621] 8.207501e-01 1.130543e-01 1.135137e-01 1.178398e-01 5.408550e-01
#>  [626] 3.290100e-01 5.263358e-01 8.269898e-01 7.767334e-01 2.269090e-01
#>  [631] 2.762173e-01 6.503063e-01 5.167225e-01 9.860253e-01 1.630830e-01
#>  [636] 5.328255e-01 5.255125e-01 6.799428e-01 3.877897e-01 6.199646e-01
#>  [641] 3.098967e-02 7.627026e-01 5.271906e-01 5.589390e-01 9.742480e-01
#>  [646] 1.576889e-01 4.521702e-01 1.008224e-01 7.741081e-01 8.209309e-01
#>  [651] 9.569165e-01 4.652360e-01 1.046835e-01 2.047927e-01 8.216972e-01
#>  [656] 9.136090e-03 9.982907e-01 6.512986e-01 3.360983e-01 5.319523e-01
#>  [661] 7.691387e-01 3.866090e-01 4.545487e-01 3.894107e-01 1.161941e-01
#>  [666] 7.749097e-01 2.351426e-01 5.417029e-01 9.495993e-01 5.215905e-02
#>  [671] 3.045963e-01 2.946884e-01 6.400297e-01 1.964604e-01 6.113878e-01
#>  [676] 2.036987e-01 3.494214e-01 5.156240e-01 8.516392e-01 3.757154e-01
#>  [681] 3.391676e-01 2.876817e-01 8.476573e-01 8.990306e-01 3.446175e-01
#>  [686] 7.038766e-01 5.606449e-01 3.948986e-01 1.676269e-01 3.560318e-01
#>  [691] 4.092531e-01 9.466584e-01 8.107880e-02 5.026558e-01 6.825868e-01
#>  [696] 8.976132e-01 3.032786e-02 6.068239e-01 5.613186e-01 7.871364e-01
#>  [701] 5.303616e-01 8.040487e-02 9.363895e-01 9.900824e-01 3.191267e-01
#>  [706] 2.332841e-01 1.767924e-01 7.082622e-01 2.274959e-01 1.198931e-01
#>  [711] 1.642899e-01 2.501723e-01 8.331256e-01 2.776798e-01 7.712836e-01
#>  [716] 3.241124e-02 7.808098e-01 1.410371e-01 9.075527e-01 3.311465e-01
#>  [721] 6.643352e-01 4.897424e-01 1.220694e-01 9.445821e-01 3.869854e-01
#>  [726] 9.500377e-01 1.780908e-01 4.436893e-01 6.564798e-01 7.530567e-01
#>  [731] 6.649227e-01 4.063791e-01 3.461324e-01 3.829748e-01 7.067588e-01
#>  [736] 6.889991e-01 4.120209e-01 8.601902e-01 2.893427e-01 6.603450e-01
#>  [741] 4.648679e-02 2.363440e-01 2.553153e-01 5.401535e-01 3.911313e-01
#>  [746] 2.327062e-01 3.593370e-01 4.716091e-01 1.101040e-01 1.161919e-01
#>  [751] 1.970560e-01 4.533116e-01 2.674756e-01 5.540283e-01 2.523654e-01
#>  [756] 7.113867e-02 7.305595e-02 3.723540e-01 4.686943e-01 5.559897e-01
#>  [761] 9.920182e-01 5.826523e-01 2.558850e-01 9.122572e-01 8.761565e-01
#>  [766] 1.333270e-01 5.690660e-01 2.555162e-01 9.008136e-01 3.238681e-01
#>  [771] 7.632489e-01 1.398708e-01 4.101197e-01 2.089683e-01 9.556451e-01
#>  [776] 3.843878e-01 3.350167e-01 9.016702e-01 7.319471e-01 3.190714e-01
#>  [781] 5.004305e-01 3.082653e-01 4.550109e-01 7.285194e-01 4.292641e-01
#>  [786] 2.363835e-01 7.240538e-01 9.211760e-01 5.490174e-01 4.843587e-01
#>  [791] 9.385143e-01 2.202831e-01 8.812278e-01 4.653990e-01 8.447010e-01
#>  [796] 3.613271e-01 9.922697e-01 2.773498e-01 2.132570e-02 2.998527e-01
#>  [801] 3.351241e-01 1.053772e-01 3.774570e-01 9.916074e-01 5.949090e-01
#>  [806] 8.746145e-01 7.056165e-01 3.767974e-01 5.187511e-01 1.257364e-01
#>  [811] 7.539881e-01 5.192379e-01 5.534506e-01 3.156905e-02 8.346753e-01
#>  [816] 7.917548e-02 4.798288e-01 1.295840e-01 1.401317e-01 6.631967e-01
#>  [821] 8.773352e-01 3.939650e-01 7.944332e-01 9.427386e-01 8.706233e-01
#>  [826] 8.827919e-01 2.602293e-01 3.720812e-02 2.105218e-01 9.879994e-01
#>  [831] 6.293165e-01 1.104228e-01 3.697614e-01 6.171525e-01 8.554555e-01
#>  [836] 3.013685e-01 4.735444e-02 7.886676e-01 3.552420e-01 3.831095e-01
#>  [841] 7.530174e-02 6.633813e-02 6.733243e-03 8.167250e-01 6.869888e-01
#>  [846] 8.888806e-01 4.078369e-01 7.882832e-01 8.279997e-02 7.538950e-01
#>  [851] 6.895798e-01 5.586327e-01 3.603814e-01 3.550381e-02 7.734797e-01
#>  [856] 4.023784e-01 4.970286e-01 3.976710e-01 7.241330e-01 7.825637e-01
#>  [861] 4.802158e-01 3.817151e-01 4.810771e-01 7.841982e-01 7.485739e-01
#>  [866] 2.148224e-01 9.603440e-01 1.319339e-01 8.371025e-01 9.158944e-01
#>  [871] 1.159962e-01 7.607178e-01 5.806022e-01 6.967158e-01 6.540920e-01
#>  [876] 8.689665e-01 8.756839e-01 4.167046e-01 7.764680e-01 7.450529e-01
#>  [881] 4.042184e-01 5.735445e-01 9.558092e-01 8.711986e-01 3.277372e-01
#>  [886] 1.202650e-01 3.976526e-01 1.448598e-01 4.421320e-01 8.132817e-01
#>  [891] 8.436767e-01 8.060262e-01 2.163138e-01 5.590138e-01 5.580483e-01
#>  [896] 9.906212e-01 4.087962e-01 2.814103e-01 6.404176e-02 6.408010e-01
#>  [901] 1.958560e-01 4.616453e-03 3.793882e-03 9.526422e-02 1.205500e-03
#>  [906] 8.109357e-02 1.174959e-03 4.088808e-03 9.855638e-04 6.753414e-02
#>  [911] 6.053228e-03 2.445469e-02 1.745406e-01 5.178342e-03 2.303324e-05
#>  [916] 3.701188e-02 1.302324e-02 1.069669e-03 7.094418e-03 1.166232e-05
#>  [921] 9.194864e-04 2.372067e-06 2.980609e-03 9.796569e-02 2.413694e-03
#>  [926] 6.570181e-02 7.717997e-02 1.269169e-02 4.857372e-04 3.023904e-03
#>  [931] 7.191309e-04 5.165416e-04 1.214400e-02 5.960518e-01 7.623432e-04
#>  [936] 4.565021e-06 6.685852e-03 1.446142e-01 1.957523e-02 6.700818e-02
#>  [941] 8.705653e-03 1.114570e-03 6.065671e-04 4.119360e-03 6.693583e-02
#>  [946] 7.209161e-04 1.152658e-04 3.204753e-06 2.624497e-02 2.064868e-03
#>  [951] 2.001216e-04 1.055459e-02 1.773473e-03 4.365464e-03 1.105043e-02
#>  [956] 4.957904e-03 4.383851e-04 2.504298e-03 2.465917e-02 5.002212e-01
#>  [961] 5.054957e-02 8.226469e-03 6.667622e-01 3.819969e-06 1.802035e-01
#>  [966] 1.028903e-01 7.717324e-05 4.725118e-01 9.141091e-04 1.850935e-02
#>  [971] 2.179709e-03 5.838389e-04 7.023623e-02 4.191123e-02 9.978415e-01
#>  [976] 7.059268e-02 2.722324e-03 1.882255e-03 8.277806e-06 6.575010e-03
#>  [981] 2.129950e-03 6.398318e-03 2.583973e-02 8.859559e-04 2.126309e-03
#>  [986] 5.518586e-03 5.272140e-02 8.671973e-03 7.986337e-04 1.113383e-03
#>  [991] 2.559369e-02 3.873669e-02 1.839037e-03 3.300770e-04 5.645723e-03
#>  [996] 1.719525e-02 6.019409e-02 2.210766e-02 1.784772e-01 4.115532e-02
#> 
#> $raw$qval
#>    [1] 0.910704143 0.938830474 0.889939559 0.734794486 0.931395527 0.891661446
#>    [7] 0.921463574 0.900369844 0.914872033 0.932729951 0.760419215 0.927855895
#>   [13] 0.911146856 0.466171446 0.848817892 0.944654121 0.945730526 0.876503443
#>   [19] 0.891576820 0.913415810 0.879776513 0.895852392 0.943500051 0.578054910
#>   [25] 0.911266443 0.944223498 0.940089029 0.772075838 0.922109560 0.926103596
#>   [31] 0.800953244 0.942357152 0.927988497 0.944313413 0.796503564 0.926290611
#>   [37] 0.927583122 0.944099810 0.853059923 0.897842132 0.939699685 0.935461881
#>   [43] 0.904383411 0.916368634 0.905152145 0.903383760 0.929373941 0.897285391
#>   [49] 0.941960095 0.884544443 0.927347697 0.911921389 0.930737073 0.848047248
#>   [55] 0.782271264 0.582236356 0.929217799 0.862052747 0.915350931 0.940995946
#>   [61] 0.369168223 0.944870652 0.905060487 0.945293206 0.899873626 0.938592502
#>   [67] 0.658672811 0.773509809 0.940201565 0.487814508 0.922291859 0.903148935
#>   [73] 0.912029858 0.877799551 0.824375170 0.933481323 0.924462760 0.946279050
#>   [79] 0.943508935 0.913771265 0.915433540 0.940990599 0.839251451 0.756958687
#>   [85] 0.913412158 0.931201415 0.859080744 0.932795433 0.929051696 0.934759404
#>   [91] 0.917450122 0.833572652 0.842513573 0.904076499 0.737505459 0.916227643
#>   [97] 0.819537996 0.915071298 0.830274821 0.922436972 0.911220750 0.944761488
#>  [103] 0.880812481 0.939989846 0.908257967 0.673606406 0.902496980 0.880907996
#>  [109] 0.928200537 0.705319084 0.909907710 0.923238097 0.782466707 0.908601921
#>  [115] 0.937719367 0.927674221 0.931927255 0.934134064 0.920987691 0.939119969
#>  [121] 0.920148252 0.804654782 0.937375240 0.939018170 0.942464147 0.902887416
#>  [127] 0.943539777 0.944931424 0.905809494 0.931689081 0.944066823 0.913821921
#>  [133] 0.918278277 0.758483743 0.932666268 0.753117846 0.932969299 0.918517487
#>  [139] 0.908478436 0.944193717 0.612282190 0.839531976 0.711386378 0.923110480
#>  [145] 0.850369888 0.899110190 0.530868408 0.945686216 0.817446356 0.719783442
#>  [151] 0.924006328 0.945643351 0.932033956 0.878423312 0.767401562 0.857143589
#>  [157] 0.868662411 0.911144647 0.794689288 0.631925082 0.925646090 0.936199816
#>  [163] 0.859811616 0.883890742 0.911315625 0.470609728 0.935377423 0.784508126
#>  [169] 0.940590483 0.937711870 0.417701406 0.942232478 0.923551088 0.943397052
#>  [175] 0.931141999 0.945041149 0.895264715 0.536753962 0.864610671 0.833564750
#>  [181] 0.828931521 0.870978297 0.937117511 0.773043164 0.919053279 0.939957546
#>  [187] 0.773775704 0.897540630 0.925316629 0.878849314 0.939130310 0.927105424
#>  [193] 0.901023923 0.890540697 0.833530796 0.861455909 0.780114857 0.866339404
#>  [199] 0.926481456 0.928388787 0.926643421 0.702926005 0.737583689 0.931316697
#>  [205] 0.429546954 0.320607422 0.907140951 0.917540343 0.945832842 0.919848860
#>  [211] 0.939706315 0.925928192 0.927215067 0.798175038 0.870417240 0.758086391
#>  [217] 0.932547134 0.824446420 0.909343330 0.944662689 0.686639215 0.946242074
#>  [223] 0.910375389 0.930745710 0.843209536 0.659405495 0.931304057 0.731474263
#>  [229] 0.938200624 0.934961374 0.870703886 0.155167918 0.909496512 0.915288907
#>  [235] 0.944083852 0.942546783 0.916046600 0.837678840 0.853602281 0.946126040
#>  [241] 0.903401401 0.863591993 0.936945030 0.884838016 0.842045976 0.572971155
#>  [247] 0.917277936 0.935344727 0.939627925 0.865651548 0.940945580 0.926783600
#>  [253] 0.943694486 0.935749368 0.904516352 0.845070481 0.368408550 0.915112858
#>  [259] 0.928770826 0.925635341 0.875536705 0.927892942 0.933859277 0.887399437
#>  [265] 0.691712358 0.934606498 0.925833020 0.837176314 0.931309641 0.877038903
#>  [271] 0.935178595 0.927577633 0.888054521 0.249048846 0.940079442 0.847899922
#>  [277] 0.427521812 0.900101894 0.810817843 0.879669574 0.927346195 0.926760981
#>  [283] 0.808997867 0.903980079 0.914487266 0.868510796 0.907040431 0.876322513
#>  [289] 0.925090298 0.867914724 0.927839048 0.928672152 0.935924839 0.784047864
#>  [295] 0.669246431 0.941022103 0.897590824 0.874976693 0.944438292 0.932706709
#>  [301] 0.882990863 0.861562541 0.586443964 0.928234092 0.715145899 0.760293400
#>  [307] 0.943164394 0.915547150 0.865039162 0.931759597 0.862133448 0.942509857
#>  [313] 0.923742882 0.908151681 0.944996061 0.858113851 0.921705025 0.941595737
#>  [319] 0.815737014 0.920978883 0.812691953 0.764676396 0.892306576 0.631711955
#>  [325] 0.921840501 0.923609018 0.930029106 0.939430890 0.886610870 0.906033079
#>  [331] 0.931530686 0.743114429 0.929204209 0.799571590 0.931126118 0.900924676
#>  [337] 0.876134246 0.946160240 0.930091733 0.918412335 0.900243376 0.859023937
#>  [343] 0.935822353 0.933585102 0.440138069 0.788547033 0.880158304 0.938476977
#>  [349] 0.893568746 0.624087241 0.771208033 0.906213089 0.928455997 0.938406193
#>  [355] 0.740345650 0.913225611 0.840091073 0.940095812 0.610259021 0.938291263
#>  [361] 0.274987933 0.811323737 0.909924415 0.925331693 0.939483828 0.911905371
#>  [367] 0.906114840 0.915489813 0.915128415 0.799846988 0.927924394 0.934196944
#>  [373] 0.891367348 0.943726591 0.841184182 0.946018491 0.941262099 0.940525970
#>  [379] 0.939727165 0.675057302 0.897903109 0.851135737 0.879227795 0.939707840
#>  [385] 0.843525761 0.944208275 0.509782846 0.930523537 0.616440453 0.892699225
#>  [391] 0.809055927 0.911619102 0.854450135 0.932663706 0.942051414 0.879083785
#>  [397] 0.735556863 0.944651181 0.902649810 0.886468799 0.857264920 0.620522418
#>  [403] 0.912670630 0.927793194 0.926212810 0.928714918 0.929252782 0.933254816
#>  [409] 0.779938167 0.904329227 0.927958252 0.908439384 0.848845357 0.896911184
#>  [415] 0.919994932 0.918862109 0.866055842 0.935573012 0.783068827 0.695584670
#>  [421] 0.781731017 0.903108165 0.943874976 0.676637185 0.915350668 0.729234767
#>  [427] 0.720911425 0.896125021 0.909436034 0.905858247 0.557184971 0.920506138
#>  [433] 0.754511691 0.945405102 0.913490371 0.938153585 0.883198360 0.945378424
#>  [439] 0.908869158 0.908983330 0.925081808 0.671529095 0.945654408 0.887941883
#>  [445] 0.937824710 0.123924487 0.799167006 0.925710152 0.936291221 0.399623435
#>  [451] 0.874079043 0.912552734 0.898900516 0.747291853 0.776692631 0.944215626
#>  [457] 0.919902290 0.525549582 0.868031270 0.917958606 0.923816385 0.491515088
#>  [463] 0.826001914 0.913285693 0.946142672 0.934121075 0.903535549 0.910570743
#>  [469] 0.769440984 0.855804830 0.892468926 0.727077995 0.942072377 0.924620765
#>  [475] 0.802781794 0.810282919 0.929385594 0.936454462 0.836254927 0.945296646
#>  [481] 0.929801829 0.844965816 0.919317210 0.929518844 0.395556537 0.346239256
#>  [487] 0.939601731 0.862124954 0.585704130 0.919517716 0.854631151 0.429847032
#>  [493] 0.883990081 0.942011885 0.033115364 0.851563725 0.932611253 0.851904793
#>  [499] 0.930361892 0.885500075 0.943391064 0.933190811 0.838285215 0.945909831
#>  [505] 0.869878839 0.735217751 0.797566095 0.935651396 0.842691649 0.850660104
#>  [511] 0.305454046 0.877560693 0.873313997 0.944556413 0.926998006 0.936553105
#>  [517] 0.925820968 0.928807101 0.929289786 0.836988782 0.900469415 0.933522913
#>  [523] 0.884084739 0.937689588 0.944547157 0.704483299 0.940598038 0.838853697
#>  [529] 0.905833508 0.940640743 0.836567477 0.840895582 0.943315258 0.923900675
#>  [535] 0.719299489 0.897174789 0.932840112 0.818432926 0.912734455 0.932640950
#>  [541] 0.926073283 0.929928097 0.919604314 0.945641598 0.810319289 0.943844977
#>  [547] 0.904068697 0.917841909 0.472836903 0.927725415 0.920791178 0.936877165
#>  [553] 0.850160386 0.927539743 0.749063941 0.899849343 0.405347532 0.892579915
#>  [559] 0.920481344 0.919792542 0.832105762 0.945495607 0.903979356 0.913935968
#>  [565] 0.912362218 0.853625072 0.935757141 0.939906434 0.910761696 0.882143365
#>  [571] 0.869506190 0.888360262 0.893303088 0.922833848 0.888457382 0.870569589
#>  [577] 0.914884810 0.561239289 0.590589389 0.841687773 0.796635934 0.939557747
#>  [583] 0.738208453 0.706841815 0.921402740 0.884842211 0.940569725 0.922740332
#>  [589] 0.928680243 0.898062876 0.933382520 0.941005143 0.792343886 0.863151976
#>  [595] 0.517334578 0.897311957 0.892143951 0.924933721 0.881603825 0.897851395
#>  [601] 0.930740086 0.763130638 0.918515424 0.917475000 0.940926079 0.846754967
#>  [607] 0.764794793 0.936949639 0.572237516 0.937031317 0.939706447 0.931219879
#>  [613] 0.928138444 0.791110114 0.237354996 0.925736837 0.933097512 0.663735141
#>  [619] 0.935732079 0.935767480 0.935352874 0.665884587 0.666786287 0.675043985
#>  [625] 0.905073460 0.852940163 0.902709629 0.935809335 0.931938729 0.800002592
#>  [631] 0.829621829 0.919768446 0.901078660 0.945599386 0.741929441 0.903780587
#>  [637] 0.902572068 0.922996193 0.872386315 0.916170989 0.353295541 0.930773341
#>  [643] 0.902852062 0.907861744 0.944977943 0.735437014 0.888530726 0.639944316
#>  [649] 0.931723671 0.935366196 0.944037162 0.891321040 0.648557087 0.783089114
#>  [655] 0.935422578 0.139446030 0.946231837 0.919880885 0.855593750 0.903637864
#>  [661] 0.931312833 0.872046459 0.889049299 0.872850002 0.671951317 0.931789476
#>  [667] 0.805644482 0.905207959 0.943630248 0.479027127 0.843003651 0.838577244
#>  [673] 0.918585087 0.775950589 0.915094857 0.782177886 0.860330794 0.900888797
#>  [679] 0.937551207 0.868823181 0.856713318 0.835293246 0.937276254 0.940647744
#>  [685] 0.858659023 0.925419259 0.908116340 0.874395043 0.747156152 0.862567636
#>  [691] 0.878264297 0.943465030 0.588358374 0.898591105 0.923271580 0.940559597
#>  [697] 0.348379129 0.914510877 0.908216498 0.932777780 0.903376772 0.586335357
#>  [703] 0.942880449 0.945810228 0.849073116 0.804399023 0.757080227 0.925846822
#>  [709] 0.800415584 0.678821769 0.743338633 0.815162635 0.936251950 0.830366936
#>  [715] 0.931490767 0.363609174 0.932269996 0.713160745 0.941172288 0.853750174
#>  [721] 0.921329424 0.896194745 0.682731049 0.943347800 0.872155008 0.943654794
#>  [727] 0.758423358 0.886641585 0.920462926 0.929948735 0.921393465 0.877508816
#>  [733] 0.859190511 0.870988897 0.925700811 0.923931348 0.878983110 0.938133596
#>  [739] 0.836083790 0.920891652 0.450396163 0.806441216 0.818209091 0.904961896
#>  [745] 0.873338492 0.804008427 0.863659394 0.892631974 0.659975866 0.671947170
#>  [751] 0.776476434 0.888780180 0.825027792 0.907120913 0.816474127 0.556357640
#>  [757] 0.562911617 0.867795553 0.892036347 0.907418243 0.945910249 0.911278980
#>  [763] 0.818540371 0.941457902 0.939192438 0.701524204 0.909352794 0.818326069
#>  [769] 0.940758265 0.850953357 0.930819458 0.711458960 0.878490288 0.786498050
#>  [775] 0.943966883 0.871402141 0.855195072 0.940811211 0.928073741 0.849050889
#>  [781] 0.898186071 0.844581826 0.889149492 0.927759773 0.883276871 0.806467325
#>  [787] 0.927346608 0.941991828 0.906352599 0.895161905 0.943002398 0.795218812
#>  [793] 0.939521213 0.891354961 0.937070550 0.864308416 0.945923220 0.830199380
#>  [799] 0.273224188 0.840915144 0.855234740 0.650061142 0.869349369 0.945889057
#>  [805] 0.912947742 0.939091761 0.925589474 0.869150580 0.901427369 0.689107234
#>  [811] 0.930029210 0.901510682 0.907032982 0.357539075 0.936362770 0.582593270
#>  [817] 0.894276804 0.695527799 0.711841481 0.921205010 0.939269177 0.874134853
#>  [823] 0.933354056 0.943243303 0.938829621 0.939621899 0.821027540 0.396107307
#>  [829] 0.787739138 0.945702184 0.917313726 0.660624517 0.866991892 0.915821177
#>  [835] 0.937812477 0.841588541 0.454977823 0.932899529 0.862304162 0.871028413
#>  [841] 0.570346458 0.539051902 0.113782045 0.935054962 0.923725734 0.940010665
#>  [847] 0.877893197 0.932869004 0.593436297 0.930021173 0.923990534 0.907815891
#>  [853] 0.864000767 0.384948058 0.931671987 0.876441434 0.897560587 0.875161390
#>  [859] 0.927353971 0.932411530 0.894352996 0.870618239 0.894522194 0.932542902
#>  [865] 0.929558783 0.791100763 0.944225758 0.699320152 0.936535578 0.941676827
#>  [871] 0.671575385 0.930605251 0.910993587 0.924710438 0.920195743 0.938720138
#>  [877] 0.939161617 0.880180342 0.931917046 0.929249445 0.876934645 0.909996903
#>  [883] 0.943975965 0.938867549 0.852453301 0.679496575 0.875156334 0.718599998
#>  [889] 0.886287691 0.934797924 0.936998962 0.934249595 0.792241826 0.907872936
#>  [895] 0.907728250 0.945838105 0.878144829 0.832238455 0.530287094 0.918675121
#>  [901] 0.775414503 0.090992996 0.079949548 0.626777254 0.038026243 0.588402489
#>  [907] 0.037804173 0.084080432 0.036200581 0.543488530 0.107204075 0.301236531
#>  [913] 0.754714870 0.097750358 0.003113827 0.394843020 0.186714239 0.036965431
#>  [919] 0.117782133 0.001839379 0.035528696 0.001079991 0.067559383 0.633295053
#>  [925] 0.059417831 0.536656128 0.576372956 0.182829911 0.028486772 0.068132796
#>  [931] 0.032984699 0.029218906 0.176331335 0.913100134 0.033610760 0.001079991
#>  [937] 0.113343223 0.718256827 0.256550891 0.541548024 0.135054478 0.037337841
#>  [943] 0.031088841 0.084496959 0.541279819 0.033011562 0.012119802 0.001079991
#>  [949] 0.316313855 0.054016099 0.017807991 0.156873443 0.049243502 0.087777797
#>  [955] 0.163041627 0.095168633 0.027250059 0.060765760 0.302992227 0.898147796
#>  [961] 0.471210865 0.130159027 0.921593330 0.001079991 0.760577551 0.644608876
#>  [967] 0.008934499 0.892815120 0.035470934 0.246018300 0.055748644 0.030650700
#>  [973] 0.553204293 0.424901307 0.946208934 0.554455143 0.063990643 0.051092244
#>  [979] 0.001552329 0.112305823 0.055007540 0.110619317 0.312958262 0.035160320
#>  [985] 0.054952745 0.101571212 0.481703900 0.134716644 0.034100208 0.037328291
#>  [991] 0.310904784 0.405776950 0.050367765 0.023775751 0.102950390 0.232614768
#>  [997] 0.514829590 0.280433071 0.758820224 0.420460038
#> 
#> $raw$lfdr
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#>  [841] 1.000000000 1.000000000 0.341787062 1.000000000 1.000000000 1.000000000
#>  [847] 1.000000000 1.000000000 1.000000000 1.000000000 1.000000000 1.000000000
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#>  [871] 1.000000000 1.000000000 1.000000000 1.000000000 1.000000000 1.000000000
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#>  [889] 1.000000000 1.000000000 1.000000000 1.000000000 1.000000000 1.000000000
#>  [895] 1.000000000 1.000000000 1.000000000 1.000000000 1.000000000 1.000000000
#>  [901] 1.000000000 0.250729791 0.250729791 1.000000000 0.131701789 1.000000000
#>  [907] 0.049129004 0.250729791 0.049129004 1.000000000 0.250729791 1.000000000
#>  [913] 1.000000000 0.250729791 0.043640713 1.000000000 1.000000000 0.049129004
#>  [919] 0.381185395 0.010760515 0.049129004 0.001079991 0.163904258 1.000000000
#>  [925] 0.153582416 1.000000000 1.000000000 1.000000000 0.049129004 0.250729791
#>  [931] 0.049129004 0.049129004 1.000000000 1.000000000 0.049129004 0.003358153
#>  [937] 0.250729791 1.000000000 1.000000000 1.000000000 0.407330726 0.049129004
#>  [943] 0.049129004 0.250729791 1.000000000 0.049129004 0.049129004 0.001079991
#>  [949] 1.000000000 0.131701789 0.049129004 1.000000000 0.131701789 0.250729791
#>  [955] 1.000000000 0.250729791 0.049129004 0.163904258 1.000000000 1.000000000
#>  [961] 1.000000000 0.381185395 1.000000000 0.001079991 1.000000000 1.000000000
#>  [967] 0.043640713 1.000000000 0.049129004 1.000000000 0.153582416 0.049129004
#>  [973] 1.000000000 1.000000000 1.000000000 1.000000000 0.163904258 0.131701789
#>  [979] 0.003358153 0.250729791 0.131701789 0.250729791 1.000000000 0.049129004
#>  [985] 0.131701789 0.250729791 1.000000000 0.381185395 0.049129004 0.049129004
#>  [991] 1.000000000 1.000000000 0.131701789 0.049129004 0.250729791 1.000000000
#>  [997] 1.000000000 1.000000000 1.000000000 1.000000000
#> 
#> $raw$statistic
#> [1] "normal"
#> 
#> $raw$param
#>      cutoff N.cens      eta0     eta0.SE       sd      sd.SE
#> [1,] 2.8708    936 0.9463188 0.007825093 1.127681 0.03123991
#> 
#> 
# }