Restricted mean survival time

Area under the Kaplan-Meier curve up to tau, RMST(tau) = integral_0^tau S(t) dt, with the variance of Klein and Moeschberger (2003) eq. (4.5.4).

Usage

Rmst(time, event, tau = NULL, alpha = 0.05)

morie_survival_rmst(time, event, tau = NULL, alpha = 0.05)

Arguments

time: observed follow-up times.
event: event indicator, 1 = event, 0 = censored.
tau: restriction horizon; defaults to the largest observed event time.
alpha: significance level for the interval.

Value

list with the RMST, its standard error, the confidence interval and the horizon used.

References

Klein, J. P. and Moeschberger, M. L. (2003). Survival Analysis, 2nd ed., Springer, eq. (4.5.4).

Examples

Rmst(time = c(1, 2, 3, 4, 5, 6, 7, 8), event = c(0, 1, 0, 1, 1, 0, 1, 0))
#> $rmst
#> [1] 5.685714
#> 
#> $se
#> [1] 0.8298091
#> 
#> $variance
#> [1] 0.6885831
#> 
#> $tau
#> [1] 8
#> 
#> $lower
#> [1] 4.059318
#> 
#> $upper
#> [1] 7.31211
#> 
#> $max_time
#> [1] 8
#> 
#> $max_event_time
#> [1] 7
#> 
#> $tau_beyond_data
#> [1] FALSE
#> 
#> $tau_beyond_last_event
#> [1] TRUE
#> 
#> $n
#> [1] 8
#> 
#> $n_events
#> [1] 4
#> 
#> $method
#> [1] "Klein and Moeschberger (2003) eq. (4.5.4); area under the Kaplan-Meier curve"
#>